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Vitashape (natural production of growth hormone and insulin)

Cardio CPS (CoQ10 etc)

 

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AC Essence 1000 & 5000

NaturextTM Immune+ AC Essence is made from 
Antrodia Camphorata Mycelia, a Rare Fungus found 
naturally only in Taiwan and have been used by the 
Chinese as a Cancer Preventive Health Supplement 
for more than 50 years.

Antrodia Camphorata is rich in Flavonoids, Terpenoids, 
Polyphenolics and Polysaccharides. The known main Bioactive 
Compounds found in AC are: Polysaccharides, Superoxide
Dismutase (SOD), and Triterpenes.

Triterpenes, the most important Bioactive Ingredient found 
in AC, is a compound which exhibits Anti-Cancer, Anti-Virus,
Anti-Oxidant, Hepatoprotection and Cholesterol Inhibition 
Properties.     

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Antrodia Camphorata (AC) is also commonly called the King of Lingzhi. AC is a rare medicinal fungus that grows naturally inside the Cinnamonum Kanehirae Tree Trunk, a native tree species of Taiwan.

Antrodia Camphorata, is a precious Traditional Chinese Herbal Medicine and shows several Pharmacological Effects including the inhibition of proliferation and growth in cancer cells, the inhibition of inflammatory response, the antioxidant and free radical-scavenging activities and the prevention of hepatotoxicity.

New Anti Cancer compound isolated from AC
Recently, scientists isolated an anti cancer compound in AC and patented and named the new bio-active compound Antroquinonol1. Various laboratory tests using AntroquinonolTM show that it was effective against a wide range of cancerous cells1. In 2010 March, AntroquinonolTM was recognized as Breakthrough Drug by the Chinese Ministry of Science and Technology.Antroquinonol™ comes with 6 FDA patents and has been approved by the US FDA to enter into first stage clinical trial.  

References: 1: Planta Med. 2007 Oct;73(13):1412-5. Epub 2007 Oct 11."A new cytotoxic agent from solid-state fermented mycelium of Antrodia Camphorata." 

Potentially more potent than Ganoderma Lucidium

Antrodia Camphorata (AC) has been proven to be more potent than Ganoderma Lucidium (Lingzhi) in pharmacological activities. Compared to the well known Ganoderma Licudium (Lingzhi) where less than 50 types of Triterpenes are found, AC contains more than 200 types of Triterpenes. In addition, the concentration of Triterpenes found in AC is 10-15 times higher than Ganoderma Lucidium.  

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Recently, scientists discovered and patented new active anti-cancer compound Antroquinonol. Antroquinonol is a unique compound found only in AC. Various clinical tests using Antroquinonol proved it effective against cancerous cells.

Naturext Immune+ AC Essence™ also uses a patented solid state fermentation process to cultivate Antrodia Camphorata to ensure highest quality and consistency in its manufacturing process. In vitro experiments have shown that the cultivated Naturext Immune+ AC EssenceTM with active anti cancer compound Antroquinonol (0.2% w/w) demonstrated superior anti cancer cell viability performance against wild Antrodia Camphorata.

Antroquinonol™
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Isolated from Antrodia Camphorata- High safety, high performance anti cancer compound.

Pharmacological Properties and Modes of Actions:

AntroquinonolTM could inhibit proferation of liver, lung, breast and prostate cancer cells. Antroquinonol™ induced S phase arrest of HepG2 cells when they are pretreated with synchronization. After synchronization with Antroquinonol, it decreases all cell cycle regulatory protein and cell growth related protein (including cyclin A, cyclin D, cyclin E, cdk2, cdk4, Rb, p53, Akt and MAPK). Antroquinonol inhibits protein synthesis through translation related protein 4E-BP1 and elF4E.

Antroquinonol™ for the treatment of multiple forms of cancer has been proven in vivo. The compound has passed in-vivo efficacy, ADME/toxicology for at least three kinds of cancer (NSCLC, liver and breast cancer) compared with the chemotherapy drugs Mitomycin and Taxol as positive control. No drug resistance was observed during in-vivo studies. This indicates that the drug can be considered a long-term orally-administered cancer therapy.  

AC Product Information, Indications, Ingredients and Application

Product Information

  • Powder of cultured Antrodia Camphorata Mycelia.

Indications

  • Anti-allergenic, strengthen immune function
  • Anti-cancer, chemoprevention
  • Anti-fatigue, anti-oxidation, anti-LDL cholesterol synthesis
  • Anti-viral Hepatitis, Anti-hepatoxication, Hepatoprotection
  • Treatment of Autoimmune diseases

Active Ingredients

  • Triterpenes
  • Antroquinonol (0.2% w/w) 

Application

Hepatic Disorders                Conditions                       AC Essence Rx         
Fatty Liver  Liver Inflammation  500mg bid
Hepatitis B Carrier  Seroconversion  1000mg bid 
Hepatitis B  Active  1500mg bid 
Liver Fibrosis    2000mg bid 
Liver Cirrhosis    2500mg bid 
Auto Immune Diseases  Durations      AC Essence Rx 
Psoriasis  4-6 months  2000mg bid 
Rheumatoid Arthritis  4-6 months   1000mg bid 
Systemic Lupus (SLE)   4-6 months  2500mg bid 
Cancer*   Treatment Stage:  AC 5000 Rx 
Cancer Stage 1   Pre/Post Chemotherapy  500mg bid  
Cancer Stage 2   Pre/Post Chemotherapy   1000mg bid   
Cancer Stage 3    Pre/Post Chemotherapy   1500mg bid  
Cancer Stage 4    Pre/Post Chemotherapy   2000mg bid  
Cancer All Stages    Adjuvant Chemotherapy  1000mg bid  
Cancer Survivor    Chemoprevention  500mg once 

Chronic Hepatitis B - Detail Complimentary & Adjuvant Application Chart: 

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牛樟芝也被称为“灵芝之王”
 
牛樟芝属于菌类,是珍贵的药用真菌,寄生于台湾独有的牛樟树树干内。牛樟芝是一种珍贵的传统中药,并有研究显示
对肿瘤细胞有抑制其增殖和生长,抑制炎症反应,抗氧化,清除自由基活性和保肝等若干个药理作用。 牛樟芝,因具有
药用价值而闻名,用于中药治疗在台湾已有50多年之久。牛樟芝含有丰富的异黄铜,三萜类化合物,多酸类和多糖体。
 
在牛樟芝里发现的生物活性化合物:多糖体,超氧化物歧化酶(SOD)和三萜类。其中,三萜类是在牛樟芝里发现的最
重要的生物活性成分化合物,它具有抗癌,抗病毒,抗氧化,保肝和抑制胆固醇的作用。
 
从牛樟芝里分离出新的抗癌化合物
 
近年来,科学家从牛樟芝上面分离出一种抗癌化合物和获得专利并命名为新的生活性化合物 Antroquinonol1 。
AntroquinonolTM 的各种体外试验显示,它对多项癌症具有一定的效果。2010年3月,中国科技技术部承认
AntroquinonolTM为突破性新药。 
 
AntroquinonolTM 配备了6项美国FDA专利,美国FDA批准进入临床试验第一阶段。
 
参考资料:1:Planta Med. 2007 Oct; 73(13): 1412-5. Epub 2007 Oct 11.
 
牛樟芝的药理活性远高于灵芝
 
牛樟芝的三萜类含量远超于灵芝两者相比较,灵芝发现的三萜类不超过50种,而牛樟芝发现的三萜类超过了200种。
此外,在牛樟芝的三萜类含量是灵芝的10-15倍。
 
AntroquinonolTM MTT ASSAY 人体癌细胞体外试验: 

Antroquinonol    MTT ASSAY*:   IC 50  (ug/ml)  

Colon cancer  
WiDr  

0.92  

Osteosarcoma (Bone) 
MG-63  

2.09  

Pancreatic 
BxPC-3  

1.44  

Oral Squamous Cell Carcinoma   
SCC-25  

1.05  

Bladder Cancer  
TSGH 8301  

1.05  

Gastric Cancer 
TSGH 9201  

1.32  

Lymphoma 
U937  

9.71  

Squamous Carcinoma (Skin)  
A431  

0.18  

Serous Cystaden Carcinoma (Ovarian) 
ES-2  

0.80  

Hormone Sensitive Hepatoma   
Hep 3B  

0.05  

Non-hormone Sensitive Hepatoma
HepG2  

1.68  

Non Small Cell Lung Cancer 
A459  

0.45  

Hormone sensitive Prostate Cancer 
LNCaP  

2.38  

Primitive neuroectodermal tumor  
SK-N-MC P10  

0.05  

Non-hormone sensitive Prostate Cancer  
DU145  

1.81  

Hormone Sensitive Breast Cancer  
MCF-7  

0.85  

Non-hormone Sensitive Breast Cancer  
MDA-MB-231  

1.03  

Toxicology studies completed to date have shown toxic effects present only after administration of 30-50 times 
effective dosage. 

Such symptoms include diarrhea and non-systemic toxic reactions. Compared to other anti-cancer drugs on the market, Antroquinonol® is the only such natural compound that does not elicit side effects.PD/PK studies have shown that Antroquinonol® bioactivity begins immediately upon being absorbed through the mucosa, allowing for convenient oral administration.

Furthermore, studies have shown that the drug does not remain in the body after a period of 13-15 hours.


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US FDA Patent Information:

Link to more information on product  scientific papers


Link to Antrodia Camphorata Clinical Papers


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